🇵🇱Poland @Bartosz Pijet

    use Drupal\profile\Entity\Profile;

    $profile = Profile::load(123123);
    $addresses = $profile->get('address');
    $addresses->setValue(array(
        'langcode' => 'pl',
        'country_code' => 'PL',
        'locality' => 'Gniezno',
        'postal_code' => '11-500',
        'address_line1' => 'Nieznana',
        'address_line2' => '17/28',
        'given_name' => 'Piotr',
        'family_name' => 'Kowalski',
    ));
    $profile->save();
    
    // Debug print so you can validate that it is working.
    ksm($profile->get('address'));