Remote instance does not support DRD

Problem/Motivation

Dashboard looses connectivity with agents. Does not show correct versions etc for domains.
drush drd:ping shows
drd_action_ping [drd_domain/25]: Remote instance does not support DRD.
Agent is installed and up to date on all domains

Steps to reproduce

Dashboard and agents all at latest 4.1 version
I have to remove and recreate each domain to get the Dashboard to recognize it again
After a while: days/weeks, the "Remote instance does not support DRD" starts happening again and dashboard looses connectivity with domain.

Proposed resolution

Remaining tasks

User interface changes

API changes

Data model changes