Slow database queries

I'm seeing some very slow queries. Are there any patches or advice to speed up performance. It seems to be entirely database related.

I'm seeing slow database performance using Maria DB "groups_field_data"."label" AS "groups_field_data_label", "group__field_learning_pat | 0.000 |
| 75690 | opigno_web | localhost | opigno | Query | 20 | Sending data | SELECT DISTINCT "groups_field_data"."label" AS "groups_field_data_label", "group__field_learning_pat | 0.000
For instance.