If entity_reports.settings doesn't exist, entity reports pages are displaying some PHP warning:
Warning: foreach() argument must be of type array|object, null given in Drupal\entity_reports\Form\EntityReportsSettingsForm->buildForm() (line 123 of modules/contrib/entity_reports/src/Form/EntityReportsSettingsForm.php).Warning: foreach() argument must be of type array|object, null given in Drupal\entity_reports\Controller\EntityReportsController->__construct() (line 81 of modules/contrib/entity_reports/src/Controller/EntityReportsController.php).Logged as administrative user, you should:
Validate if entity reports fields exists before using it.
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Closed: cannot reproduce
2.0
Code
I think the configuration is always there, It will never be NULL. As it is defined in the config/install/schema.yml file.